Epidermal Growth Factor Receptor (EGFR) targeted polymer based nanostructures are promising tools for selective treatment of EGFR overexpressing cells. GE11 peptide is dodecapeptide that was shown to be able to mediate specific targeting to EGFR expressing tumors in vivo and have high binding capacity to EGFR and low mitogenic activity. Poly(lactic-co-glycolic acid) (PLGA) is an intersting polymer due to its long clinical experience, strenght, favourable degradation characteristics and possibilities for sustained drug delivery .
Peptide-polymer conjugates as tools to selectively target EGFR / N. Vidovic, M. Biagiott, B. Colzani, I. Genta, G. Speranza. ((Intervento presentato al convegno met4pharm tenutosi a Rovinj nel 2015.
Peptide-polymer conjugates as tools to selectively target EGFR
N. VidovicPrimo
;G. SperanzaUltimo
2015
Abstract
Epidermal Growth Factor Receptor (EGFR) targeted polymer based nanostructures are promising tools for selective treatment of EGFR overexpressing cells. GE11 peptide is dodecapeptide that was shown to be able to mediate specific targeting to EGFR expressing tumors in vivo and have high binding capacity to EGFR and low mitogenic activity. Poly(lactic-co-glycolic acid) (PLGA) is an intersting polymer due to its long clinical experience, strenght, favourable degradation characteristics and possibilities for sustained drug delivery .
| File | Dimensione | Formato | |
|---|---|---|---|
|
POSTER-ROVINJ.pdf
accesso riservato
Descrizione: poster
Tipologia:
Publisher's version/PDF
Dimensione
1.05 MB
Formato
Adobe PDF
|
1.05 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
