The low surface roughness of disposable contact lenses made of a new siloxane-hydrogel loaded with hyaluronic acid is reported, as studied by atomic force microscopy (AFM). Before the wear, the surface is characterized by out-of-plane and sharp structures, with maximum height of about 10 nm. After a wear of 8 h, evidence of two typical morphologies is provided and discussed. One morphology (sharp type) has a similar aspect as the unworn lenses with a slight increase in both the height and the number of the sharp peaks. The other morphology (smooth type) is characterized by troughs and bumpy structures. Wettability and clinical performances are also discussed, the latter deduced by the ocular-surface-disease index (OSDI). The main finding arising from this work is the indication of correlation between the change of the OSDI before and after wear and the lens surface characteristics obtained by AFM.
Surface properties and wear performances of siloxane-hydrogel contact lenses / M. Bettuelli, S. Trabattoni, M. Fagnola, S. Tavazzi, L. Introzzi, S. Farris. - In: JOURNAL OF BIOMEDICAL MATERIALS RESEARCH. PART B, APPLIED BIOMATERIALS.. - ISSN 1552-4973. - 101:8(2013 Nov), pp. 1585-1593.
|Titolo:||Surface properties and wear performances of siloxane-hydrogel contact lenses|
|Parole Chiave:||new siloxane-hydrogel material; atomic force microscopy; disposable contact lenses; wettability; wear of contact lenses; ocular surface disease index|
|Settore Scientifico Disciplinare:||Settore AGR/15 - Scienze e Tecnologie Alimentari|
Settore CHIM/05 - Scienza e Tecnologia dei Materiali Polimerici
|Data di pubblicazione:||nov-2013|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1002/jbm.b.32901|
|Appare nelle tipologie:||01 - Articolo su periodico|