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Covalent modifications of albumin Cys34 as a biomarker of mild oxidative dtress / G. Aldini, K. Yeum, G. Vistoli - In: Biomarkers for antioxidant defense and oxidative damage: principles and practical applications / [a cura di] G. Aldini, K.-J. Yeum, E. Niki, R.M. Russell. - [s.l] : Wiley-Blackwell, 2010. - ISBN 9780813815350. - pp. 229-241 [10.1002/9780813814438.ch14]

Covalent modifications of albumin Cys34 as a biomarker of mild oxidative dtress

G. Aldini;G. Vistoli
2010
Albumin Cys34 and its oxidized forms -potential biomarkers of oxidative damage; Covalent modifications of albumin Cys34 -as mild oxidative stress biomarker; CYS34 acting -as an antioxidant; Cys34, reactive antioxidant and detoxifying residues -of electrophilic species; Direct infusion MS, infusing solutions of isolated albumin dissolved in denaturing solvent; Human serum albumin (HSA), abundant protein in plasma -60% of total circulating proteins; LC-ESI-MS approach for identification -of unknown and predicted modifications of Cys34; Mercaptoalbumin, markers of antioxidant status; Molecular mechanisms of mercaptoalbumin -as extracellular antioxidant, main oxidation products; Serum albumin concentration and mortality risk-inverse relationship
Settore CHIM/08 - Chimica Farmaceutica
2010
http://onlinelibrary.wiley.com/book/10.1002/9780813814438
Book Part (author)
03 - Contributo in volume
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/425310
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