We compared the laboratory and clinical findings of 179 patients with essential thrombocythemia (ET) and 77 with polycythemia vera (PV) classified according to the presence of the JAK2 V617F mutation. A gradient between patients with JAK2 wild-type ET, JAK2 V617F ET and PV (all carrying the JAK2 mutation) was observed. The rate of thrombotic complications in JAK2-positive ET was significantly higher than in wild-type ET and not statistically different from that of PV patients.
|Titolo:||Transcriptional features of multiple myeloma patients with chromosome 1Q gain|
|Parole Chiave:||Essential thrombocythemia; JAK2 mutation; Polycythemia vera; Thrombosis|
|Settore Scientifico Disciplinare:||Settore MED/15 - Malattie del Sangue|
|Data di pubblicazione:||2007|
|Digital Object Identifier (DOI):||10.3324/haematol.10634|
|Appare nelle tipologie:||01 - Articolo su periodico|