We examined whether phosphorylation of Aiolos in primary human lymphocytes is part of the malignant transformation in leukemia. By analyzing mutations at a restriction site we show here that impairment of Aiolos activity in human leukemia is not based on deficient phosphorylation as had been demonstrated in experiments in vitro.
Genome-wide analysis of DNA copy number changes in multiple myeloma using high-density SNP arrays / L. Mosca, L. Agnelli, D. Ronchetti, S. Fabris, K. Todoerti, S. Bicciato, L. Baldini, F. Morabito, G. Lambertenghi Deliliers, A. Neri. - In: HAEMATOLOGICA. - ISSN 0390-6078. - 92:Suppl. 1(2007), pp. 260-260 (Astract nr. 0697). ((Intervento presentato al 12. convegno Annual Congress of the European Hematology Association tenutosi a Vienna nel 2007.
Genome-wide analysis of DNA copy number changes in multiple myeloma using high-density SNP arrays
L. AgnelliSecondo
;D. Ronchetti;S. Fabris;K. Todoerti;L. Baldini;G. Lambertenghi DeliliersPenultimo
;A. NeriUltimo
2007
Abstract
We examined whether phosphorylation of Aiolos in primary human lymphocytes is part of the malignant transformation in leukemia. By analyzing mutations at a restriction site we show here that impairment of Aiolos activity in human leukemia is not based on deficient phosphorylation as had been demonstrated in experiments in vitro.
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