The asymmetric synthesis of polyfunctionalized piperidine-and pyrrolidine-based scaffolds, specifically designed for the preparation of cyclic, conformationally constrained beta-amino acids, is realized combining a biocatalytic access to a versatile chiral building block with a wide range of transformations based on olefin metathesis.
An efficient enantioselective approach to cyclic beta-amino acid derivatives via olefin metathesis reactions / G. Lesma, B. Danieli, A. Sacchetti, A. Silvani. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - 71:8(2006), pp. 3317-3320.
An efficient enantioselective approach to cyclic beta-amino acid derivatives via olefin metathesis reactions
G. LesmaPrimo
;B. DanieliSecondo
;A. SacchettiPenultimo
;A. SilvaniUltimo
2006
Abstract
The asymmetric synthesis of polyfunctionalized piperidine-and pyrrolidine-based scaffolds, specifically designed for the preparation of cyclic, conformationally constrained beta-amino acids, is realized combining a biocatalytic access to a versatile chiral building block with a wide range of transformations based on olefin metathesis.File in questo prodotto:
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