Ochratoxin A (OTA) is a nephrotoxic and potentially carcinogenic mycotoxin produced by several species of Aspergillus and Penicillium. It is one of the major mycotoxins contaminating grain, grapes and a variety of food products, and the development of methods for reducing pre- and post-harvest contamination has drawn considerable attention. In the current study, we isolated and sequenced the genome of a novel free-living Acinetobacter strain able to degrade OTA. Biochemical studies suggest that the degradation reaction proceeds via peptide bond hydrolysis.
Draft genome sequence of acinetobacter sp. neg1 capable of degrading ochratoxin A / F. Fanelli, M. Chiara, V.C. Liuzzi, M. Haidukowski, M. Tristezza, M. Caterina, A.M. D'Erchia, G. Pesole, D.S. Horner, G. Mule. - In: FEMS MICROBIOLOGY LETTERS. - ISSN 0378-1097. - 362:7(2015 Apr), pp. fnv004.1-fnv004.4. [10.1093/femsle/fnv004]
Draft genome sequence of acinetobacter sp. neg1 capable of degrading ochratoxin A
M. ChiaraSecondo
;D.S. HornerPenultimo
;
2015
Abstract
Ochratoxin A (OTA) is a nephrotoxic and potentially carcinogenic mycotoxin produced by several species of Aspergillus and Penicillium. It is one of the major mycotoxins contaminating grain, grapes and a variety of food products, and the development of methods for reducing pre- and post-harvest contamination has drawn considerable attention. In the current study, we isolated and sequenced the genome of a novel free-living Acinetobacter strain able to degrade OTA. Biochemical studies suggest that the degradation reaction proceeds via peptide bond hydrolysis.Pubblicazioni consigliate
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