Ochratoxin A (OTA) is a nephrotoxic and potentially carcinogenic mycotoxin produced by several species of Aspergillus and Penicillium. It is one of the major mycotoxins contaminating grain, grapes and a variety of food products, and the development of methods for reducing pre- and post-harvest contamination has drawn considerable attention. In the current study, we isolated and sequenced the genome of a novel free-living Acinetobacter strain able to degrade OTA. Biochemical studies suggest that the degradation reaction proceeds via peptide bond hydrolysis.

Draft genome sequence of acinetobacter sp. neg1 capable of degrading ochratoxin A / F. Fanelli, M. Chiara, V.C. Liuzzi, M. Haidukowski, M. Tristezza, M. Caterina, A.M. D'Erchia, G. Pesole, D.S. Horner, G. Mule. - In: FEMS MICROBIOLOGY LETTERS. - ISSN 0378-1097. - 362:7(2015 Apr), pp. fnv004.1-fnv004.4. [10.1093/femsle/fnv004]

Draft genome sequence of acinetobacter sp. neg1 capable of degrading ochratoxin A

M. Chiara
Secondo
;
D.S. Horner
Penultimo
;
2015

Abstract

Ochratoxin A (OTA) is a nephrotoxic and potentially carcinogenic mycotoxin produced by several species of Aspergillus and Penicillium. It is one of the major mycotoxins contaminating grain, grapes and a variety of food products, and the development of methods for reducing pre- and post-harvest contamination has drawn considerable attention. In the current study, we isolated and sequenced the genome of a novel free-living Acinetobacter strain able to degrade OTA. Biochemical studies suggest that the degradation reaction proceeds via peptide bond hydrolysis.
No
English
Acinetobacter; degradation; ochratoxin A
Settore BIO/11 - Biologia Molecolare
Articolo
Esperti anonimi
Ricerca di base
Pubblicazione scientifica
apr-2015
Wiley
362
7
fnv004
1
4
4
Pubblicato
Periodico con rilevanza internazionale
pubmed
crossref
NON aderisco
info:eu-repo/semantics/article
Draft genome sequence of acinetobacter sp. neg1 capable of degrading ochratoxin A / F. Fanelli, M. Chiara, V.C. Liuzzi, M. Haidukowski, M. Tristezza, M. Caterina, A.M. D'Erchia, G. Pesole, D.S. Horner, G. Mule. - In: FEMS MICROBIOLOGY LETTERS. - ISSN 0378-1097. - 362:7(2015 Apr), pp. fnv004.1-fnv004.4. [10.1093/femsle/fnv004]
none
Prodotti della ricerca::01 - Articolo su periodico
10
262
Article (author)
Periodico con Impact Factor
F. Fanelli, M. Chiara, V.C. Liuzzi, M. Haidukowski, M. Tristezza, M. Caterina, A.M. D'Erchia, G. Pesole, D.S. Horner, G. Mule
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/281738
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