Ochratoxin A (OTA) is a nephrotoxic and potentially carcinogenic mycotoxin produced by several species of Aspergillus and Penicillium. It is one of the major mycotoxins contaminating grain, grapes and a variety of food products, and the development of methods for reducing pre- and post-harvest contamination has drawn considerable attention. In the current study, we isolated and sequenced the genome of a novel free-living Acinetobacter strain able to degrade OTA. Biochemical studies suggest that the degradation reaction proceeds via peptide bond hydrolysis.

Draft genome sequence of acinetobacter sp. neg1 capable of degrading ochratoxin A / F. Fanelli, M. Chiara, V.C. Liuzzi, M. Haidukowski, M. Tristezza, M. Caterina, A.M. D'Erchia, G. Pesole, D.S. Horner, G. Mule. - In: FEMS MICROBIOLOGY LETTERS. - ISSN 0378-1097. - 362:7(2015 Apr), pp. fnv004.1-fnv004.4.

Draft genome sequence of acinetobacter sp. neg1 capable of degrading ochratoxin A

M. Chiara
Secondo
;
D.S. Horner
Penultimo
;
2015-04

Abstract

Ochratoxin A (OTA) is a nephrotoxic and potentially carcinogenic mycotoxin produced by several species of Aspergillus and Penicillium. It is one of the major mycotoxins contaminating grain, grapes and a variety of food products, and the development of methods for reducing pre- and post-harvest contamination has drawn considerable attention. In the current study, we isolated and sequenced the genome of a novel free-living Acinetobacter strain able to degrade OTA. Biochemical studies suggest that the degradation reaction proceeds via peptide bond hydrolysis.
Acinetobacter; degradation; ochratoxin A
Settore BIO/11 - Biologia Molecolare
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/281738
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