Aims: To investigate the effect of prolonged consumption of a synbiotic milk (Synbiotic) containing Lactobacillus acidophilus (strain 74-2, 107 CFU ml1), Bifidobacterium lactis (strain 420, 107 CFU ml1) and 2% inulin on colonic ecosystem in healthy humans. Methods and Results: A group of 26 healthy subjects, aged 22–47 years, participated in a 6-week placebo-controlled dietary intervention study. After a 2-week baseline period, in which all volunteers consumed 500 ml day1 of 2% skimmed milk (Placebo), the study was designed as a randomized, double-blind, two-armed parallel study in which 4-week consumption of 500 ml day portions of Synbiotic or Placebo were compared. Faecal microbial counts, pH, l-lactic acid and bile acid concentrations were assessed before and after the intervention. Synbiotic consumption significantly decreased faecal dry weight (P < 0·01) and l-lactic acid (P < 0·05) concentration, while significantly increased faecal bifidobacteria (P < 0·05) and lactobacilli (P < 0·01) counts. Conclusion: The tested synbiotic milk showed its synbiotic nature by enhancing the growth of bifidobacteria and lactobacilli. Significance and Impact of the Study: Scientific support to functional effect of a synbiotic milk.

Effects of a synbiotic milk product on human intestinal ecosystem / M.C. Casiraghi, E. Canzi, R. Zanchi, E. Donati, L. Villa. - In: JOURNAL OF APPLIED MICROBIOLOGY. - ISSN 1364-5072. - 103:2(2007), pp. 499-506.

Effects of a synbiotic milk product on human intestinal ecosystem

M.C. Casiraghi
Primo
;
E. Canzi
Secondo
;
R. Zanchi;
2007

Abstract

Aims: To investigate the effect of prolonged consumption of a synbiotic milk (Synbiotic) containing Lactobacillus acidophilus (strain 74-2, 107 CFU ml1), Bifidobacterium lactis (strain 420, 107 CFU ml1) and 2% inulin on colonic ecosystem in healthy humans. Methods and Results: A group of 26 healthy subjects, aged 22–47 years, participated in a 6-week placebo-controlled dietary intervention study. After a 2-week baseline period, in which all volunteers consumed 500 ml day1 of 2% skimmed milk (Placebo), the study was designed as a randomized, double-blind, two-armed parallel study in which 4-week consumption of 500 ml day portions of Synbiotic or Placebo were compared. Faecal microbial counts, pH, l-lactic acid and bile acid concentrations were assessed before and after the intervention. Synbiotic consumption significantly decreased faecal dry weight (P < 0·01) and l-lactic acid (P < 0·05) concentration, while significantly increased faecal bifidobacteria (P < 0·05) and lactobacilli (P < 0·01) counts. Conclusion: The tested synbiotic milk showed its synbiotic nature by enhancing the growth of bifidobacteria and lactobacilli. Significance and Impact of the Study: Scientific support to functional effect of a synbiotic milk.
Bifidobacteria; Faecal bile acids; Inulin; Lactic acid bacteria; Synbiotic
Settore AGR/16 - Microbiologia Agraria
Settore BIO/09 - Fisiologia
2007
Article (author)
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/26333
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 26
  • ???jsp.display-item.citation.isi??? 18
social impact