A simple, efficient and general two step procedure, through a sequential Ugi reaction followed by a BischlereNapieralski/ heterocyclization tandem closure, to give novel 6,11-dihydro-5H-imidazo[10,50:1,2] pyrido[3,4-b]indol-2-ium salt derivatives, is described. By changing the amine and the acid components with ammonium formate, the same procedure affords 6,11-dihydro-5H-imidazo[10,50:1,2]pyrido[3,4-b] indole derivatives.

Multicomponent access to novel dihydroimidazo[1′,5′:1,2]pyrido[3,4-b]indol-2-ium salts and indoles by means of Ugi/Bischler–Napieralski/heterocyclization two step strategy / A. Silvani, G. Lesma, S. Crippa, V. Vece. - In: TETRAHEDRON. - ISSN 0040-4020. - 70:26(2014), pp. 3994-4001. [10.1016/j.tet.2014.04.081]

Multicomponent access to novel dihydroimidazo[1′,5′:1,2]pyrido[3,4-b]indol-2-ium salts and indoles by means of Ugi/Bischler–Napieralski/heterocyclization two step strategy

A. Silvani;G. Lesma;S. Crippa;V. Vece
2014

Abstract

A simple, efficient and general two step procedure, through a sequential Ugi reaction followed by a BischlereNapieralski/ heterocyclization tandem closure, to give novel 6,11-dihydro-5H-imidazo[10,50:1,2] pyrido[3,4-b]indol-2-ium salt derivatives, is described. By changing the amine and the acid components with ammonium formate, the same procedure affords 6,11-dihydro-5H-imidazo[10,50:1,2]pyrido[3,4-b] indole derivatives.
Carboline; Imidazolium salt; Isonitrile; Multicomponent reaction; Ugi reaction
Settore CHIM/06 - Chimica Organica
2014
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/239098
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