The in vivo release performance of a gastroresistant capsular device based on HPMCAS and prepared by injection molding (IM) was preliminarily evaluated in volunteers with respect to conventional enteric coated dosage forms. IM capsule prototypes demonstrated promising results in terms of opening time after entering the small intestine.
Preliminary in vivo evaluation of a gastroresistant capsular device prepared by injection molding / L. Zema, G. Loreti, A. Melocchi, E. Macchi, M.D. Del Curto, A. Foppoli, A. Gazzaniga - In: Proceedings of 2013 CRS annual meeting and exposition[s.l] : CRS (Controlled Release Society), 2013 Jul. (( Intervento presentato al 40. convegno Annual meeting & exposition of the controlled release society tenutosi a Honolulu nel 2013.
Preliminary in vivo evaluation of a gastroresistant capsular device prepared by injection molding
L. Zema;G. Loreti;A. Melocchi;E. Macchi;M.D. Del Curto;A. Foppoli;A. Gazzaniga
2013
Abstract
The in vivo release performance of a gastroresistant capsular device based on HPMCAS and prepared by injection molding (IM) was preliminarily evaluated in volunteers with respect to conventional enteric coated dosage forms. IM capsule prototypes demonstrated promising results in terms of opening time after entering the small intestine.
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