Forty-seven Italian patients suffering from hepatocellular carcinoma (HCC) and 58 patients with chronic active hepatitis (CAH) were screened for α 1-antitrypsin (α 1AT) levels and types and compared with a previously screened healthy Italian population. Serum α 1AT concentrations were significantly raised among the HCC patients compared to the controls, whereas the CAH group showed no differences. The incidence of non-M phenotypes (MS, MZ and S) is significantly higher in patients with HCC than in the CAH group and the controls. The mean age of HCC patients with a non-M phenotype is significantly lower than the mean age of HCC patients with an M phenotype.
Alpha 1-antitrypsin in patients with hepatocellular carcinoma and chronic active hepatitis / S. Fargion, E.C. Klasen, F. Lalatta, G. Sangalli, M. Tommasini, G. Fiorelli. - In: CLINICAL GENETICS. - ISSN 0009-9163. - 19:2(1981 Feb), pp. 134-139.
Titolo: | Alpha 1-antitrypsin in patients with hepatocellular carcinoma and chronic active hepatitis |
Autori: | FARGION, SILVIA ROSSANA (Primo) FIORELLI, GEMINO (Ultimo) |
Parole Chiave: | Adult ; Aged ; Carcinoma, Hepatocellular ; Chronic Disease ; Gene Frequency ; Hepatitis ; Humans ; Liver Neoplasms ; Middle Aged ; Phenotype ; alpha 1-Antitrypsin |
Settore Scientifico Disciplinare: | Settore MED/09 - Medicina Interna |
Data di pubblicazione: | feb-1981 |
Rivista: | |
Tipologia: | Article (author) |
Appare nelle tipologie: | 01 - Articolo su periodico |