Forty-seven Italian patients suffering from hepatocellular carcinoma (HCC) and 58 patients with chronic active hepatitis (CAH) were screened for α 1-antitrypsin (α 1AT) levels and types and compared with a previously screened healthy Italian population. Serum α 1AT concentrations were significantly raised among the HCC patients compared to the controls, whereas the CAH group showed no differences. The incidence of non-M phenotypes (MS, MZ and S) is significantly higher in patients with HCC than in the CAH group and the controls. The mean age of HCC patients with a non-M phenotype is significantly lower than the mean age of HCC patients with an M phenotype.
|Titolo:||Alpha 1-antitrypsin in patients with hepatocellular carcinoma and chronic active hepatitis|
FARGION, SILVIA ROSSANA (Primo)
FIORELLI, GEMINO (Ultimo)
|Parole Chiave:||Adult ; Aged ; Carcinoma, Hepatocellular ; Chronic Disease ; Gene Frequency ; Hepatitis ; Humans ; Liver Neoplasms ; Middle Aged ; Phenotype ; alpha 1-Antitrypsin|
|Settore Scientifico Disciplinare:||Settore MED/09 - Medicina Interna|
|Data di pubblicazione:||feb-1981|
|Appare nelle tipologie:||01 - Articolo su periodico|