Background: Declines in gastric cancer (GC) incidence and mortality have been related to improvements in diet. It is therefore important to consider dietary patterns. Design: We conducted a systematic review and meta-analysis of the literature through Medline and Embase databases. Results: We identified 16 papers, of these 9 derived dietary patterns through an a posteriori method, 5 through a priori scores, and 2 used both approaches. Eight studies that used the a posteriori approach were considered for the meta-analysis. A favorable role on GC emerged for the 'Prudent/healthy', with an odds ratio (OR) of 0.75 [95% confidence interval (CI): 0.63-0.90], for the highest versus the lowest category. Similar results emerged for separate anatomical subtypes. An unfavorable role on GC emerged for the 'Western/unhealthy' dietary pattern, with an OR of 1.51 (95% CI: 1.21-1.89). This association was weaker for the distal/NOS (not otherwise specified) category (OR = 1.36) compared with the cardia GC (OR = 2.05). Among the a priori scores, the ORs ranged from 0.2 to 0.7 for the favorable and from 1.8 to 6.9 for the unfavorable ones. Conclusion: There is a ~2-fold difference in GC risk between a 'Prudent/healthy' diet-rich in fruits and vegetables, and a 'Western/unhealthy' diet-rich in starchy foods, meat and fats.
Dietary patterns and gastric cancer risk: a systematic review and meta-analysis / P. Bertuccio, V. Rosato, A. Andreano, M. Ferraroni, A. Decarli, V. Edefonti, C. La Vecchia. - In: ANNALS OF ONCOLOGY. - ISSN 0923-7534. - 24:6(2013 Jun), pp. 1450-1458.
|Titolo:||Dietary patterns and gastric cancer risk: a systematic review and meta-analysis|
BERTUCCIO, PAOLA (Primo)
ROSATO, VALENTINA (Secondo)
EDEFONTI, VALERIA CARLA (Penultimo)
|Parole Chiave:||dietary patterns; gastric cancer; meta-analysis; review; score; Food Habits; Dietary Fats; Dietary Sucrose; Fruit; Humans; Meat; Risk Factors; Stomach Neoplasms; Vegetables|
|Settore Scientifico Disciplinare:||Settore MED/01 - Statistica Medica|
|Data di pubblicazione:||giu-2013|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1093/annonc/mdt108|
|Appare nelle tipologie:||01 - Articolo su periodico|
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