Background: Declines in gastric cancer (GC) incidence and mortality have been related to improvements in diet. It is therefore important to consider dietary patterns. Design: We conducted a systematic review and meta-analysis of the literature through Medline and Embase databases. Results: We identified 16 papers, of these 9 derived dietary patterns through an a posteriori method, 5 through a priori scores, and 2 used both approaches. Eight studies that used the a posteriori approach were considered for the meta-analysis. A favorable role on GC emerged for the 'Prudent/healthy', with an odds ratio (OR) of 0.75 [95% confidence interval (CI): 0.63-0.90], for the highest versus the lowest category. Similar results emerged for separate anatomical subtypes. An unfavorable role on GC emerged for the 'Western/unhealthy' dietary pattern, with an OR of 1.51 (95% CI: 1.21-1.89). This association was weaker for the distal/NOS (not otherwise specified) category (OR = 1.36) compared with the cardia GC (OR = 2.05). Among the a priori scores, the ORs ranged from 0.2 to 0.7 for the favorable and from 1.8 to 6.9 for the unfavorable ones. Conclusion: There is a ~2-fold difference in GC risk between a 'Prudent/healthy' diet-rich in fruits and vegetables, and a 'Western/unhealthy' diet-rich in starchy foods, meat and fats.

Dietary patterns and gastric cancer risk: a systematic review and meta-analysis / P. Bertuccio, V. Rosato, A. Andreano, M. Ferraroni, A. Decarli, V. Edefonti, C. La Vecchia. - In: ANNALS OF ONCOLOGY. - ISSN 0923-7534. - 24:6(2013 Jun), pp. 1450-1458. [10.1093/annonc/mdt108]

Dietary patterns and gastric cancer risk: a systematic review and meta-analysis

P. Bertuccio
Primo
;
V. Rosato
Secondo
;
A. Andreano;M. Ferraroni;A. Decarli;V. Edefonti
Penultimo
;
C. La Vecchia
Ultimo
2013

Abstract

Background: Declines in gastric cancer (GC) incidence and mortality have been related to improvements in diet. It is therefore important to consider dietary patterns. Design: We conducted a systematic review and meta-analysis of the literature through Medline and Embase databases. Results: We identified 16 papers, of these 9 derived dietary patterns through an a posteriori method, 5 through a priori scores, and 2 used both approaches. Eight studies that used the a posteriori approach were considered for the meta-analysis. A favorable role on GC emerged for the 'Prudent/healthy', with an odds ratio (OR) of 0.75 [95% confidence interval (CI): 0.63-0.90], for the highest versus the lowest category. Similar results emerged for separate anatomical subtypes. An unfavorable role on GC emerged for the 'Western/unhealthy' dietary pattern, with an OR of 1.51 (95% CI: 1.21-1.89). This association was weaker for the distal/NOS (not otherwise specified) category (OR = 1.36) compared with the cardia GC (OR = 2.05). Among the a priori scores, the ORs ranged from 0.2 to 0.7 for the favorable and from 1.8 to 6.9 for the unfavorable ones. Conclusion: There is a ~2-fold difference in GC risk between a 'Prudent/healthy' diet-rich in fruits and vegetables, and a 'Western/unhealthy' diet-rich in starchy foods, meat and fats.
dietary patterns; gastric cancer; meta-analysis; review; score; Food Habits; Dietary Fats; Dietary Sucrose; Fruit; Humans; Meat; Risk Factors; Stomach Neoplasms; Vegetables
Settore MED/01 - Statistica Medica
giu-2013
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/231248
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