An investigation on molybdenum metabolism by administration of molybdenum stable isotopes was performed. Fractional intestinal absorption was determined in animals by the double tracer technique. The investigated subjects were given an enriched solution of Mo-96 orally and, a few minutes later, an enriched solution of Mo-95 intravenously. Blood samples were drawn at different times following the tracer administration. The Mo-95 and Mo-96 contents in plasma samples were determined by proton nuclear activation. The described methodology offers a means for the study of molybdenum metabolism in humans without radiation risk.
Molybdenum metabolism studied by means of stable tracers / M.C. Cantone, N. Molho, L. Pirola, G. Gambarini, C. Hansen, P. Roth, E. Werner. - In: MEDICAL PHYSICS. - ISSN 0094-2405. - 19:2(1992), pp. 439-444. [10.1118/1.596831]
Molybdenum metabolism studied by means of stable tracers
M.C. CantonePrimo
;L. Pirola;G. Gambarini;
1992
Abstract
An investigation on molybdenum metabolism by administration of molybdenum stable isotopes was performed. Fractional intestinal absorption was determined in animals by the double tracer technique. The investigated subjects were given an enriched solution of Mo-96 orally and, a few minutes later, an enriched solution of Mo-95 intravenously. Blood samples were drawn at different times following the tracer administration. The Mo-95 and Mo-96 contents in plasma samples were determined by proton nuclear activation. The described methodology offers a means for the study of molybdenum metabolism in humans without radiation risk.
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