A capillary electrophoretic method, which allowed the detection and separation of the active principles of Catha edulis, i.e. cathinone, cathine and phenylpropanolamine, was developed. A suitable internal standard (nicotinamide), which permitted the quantification of the analytes reducing the variability of the migration times due to EOF changes, was identified. The analytical method was validated, assessing linearity, sensitivity and repeatability, showing optimal features for the analysis of the vegetable material. Moreover extraction conditions were investigated to achieve the exhaustion of the plant material in the fastest and most efficient way to meet the requirements of the Court.
Capillary electrophoretic and extraction conditions for the analysis of Catha edulis FORKS active principles / G. Roda, V. Liberti, S. Arnoldi, A. Argo, C. Rusconi, S. Suardi, V. Gambaro. - In: FORENSIC SCIENCE INTERNATIONAL. - ISSN 0379-0738. - 228:1-3(2013 Mar 28), pp. 154-159.
|Titolo:||Capillary electrophoretic and extraction conditions for the analysis of Catha edulis FORKS active principles|
RODA, GABRIELLA (Primo)
LIBERTI, VINCENZO (Secondo)
GAMBARO, VENIERO (Ultimo)
|Parole Chiave:||Catha edulis; Cathine; Cathinone; CE; Phenylpropanolamine|
|Settore Scientifico Disciplinare:||Settore CHIM/08 - Chimica Farmaceutica|
|Data di pubblicazione:||28-mar-2013|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.forsciint.2013.02.034|
|Appare nelle tipologie:||01 - Articolo su periodico|