The results of the analysis of some herbal products and powders adulterated with alkylindoles recovered on the Italian market between 2010 and 2011 are reported. Besides the well-known alkyindoles JWH-018 and JWH-073, other derivatives such as JWH-250 and AM-694 have been detected and for the first time in Italy 1-butyl-3-(1-(4-methyl)naphthoyl)indole (compound 1), the 4-methylnaphthoyl analogue of JWH- 073. This compound as well as the other alkylindoles has been synthesized and characterized by 1H NMR, 13C NMR, DSC, GC/MS, and elemental analysis. The quantitative analyses of the samples have been carried out by means of the GC/FID method developed in our laboratory for the analysis of herbal high products containing naphthoylindoles; the quantity of the cannabimimetic substances ranged from 6 mg/g to 47 mg/g.
Identification of 1-butyl-3-(1-(4-methyl)naphtoyl)indole detected for the first time in ‘‘herbal high’’ products on the Italian market / E. Valoti, E. Casagni, L. Dell’Acqua, M. Pallavicini, G. Roda, C. Rusconi, V. Straniero, V. Gambaro. - In: FORENSIC SCIENCE INTERNATIONAL. - ISSN 0379-0738. - 223:1/3(2012), pp. e42-e46.
|Titolo:||Identification of 1-butyl-3-(1-(4-methyl)naphtoyl)indole detected for the first time in ‘‘herbal high’’ products on the Italian market|
VALOTI, ERMANNO (Primo)
CASAGNI, ELEONORA (Secondo)
STRANIERO, VALENTINA (Penultimo)
GAMBARO, VENIERO (Ultimo)
|Parole Chiave:||1-Butyl-3-(1-(4-methyl)naphthoyl)indole; Cannabimimetic alkylindoles; herbal products; JWH-018; JWH-073|
|Settore Scientifico Disciplinare:||Settore CHIM/08 - Chimica Farmaceutica|
|Data di pubblicazione:||2012|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.forsciint.2012.08.009|
|Appare nelle tipologie:||01 - Articolo su periodico|