To study the effect of BoLA-D antigens on tuberculosis (TB) progression, Italian Friesian cattle in 4 TB positive farms were sampled. In each farm 50% of sampled animals were negative and the last 50% of sampled animals were positive to TB. The -interferon test (IFN) has been used for diagnosis of TB. BoLA DRB3 exon 2 polymorphism has been performed by PCR/RFLP. The effect of DRB3.2 alleles on TB has been estimate by multiple regression models. No significant genetic effect on -IFN secretion has been recorded.
BoLA DRB3 exon2 polymorphism in tuberculosis infected cattle / M. Longeri, L. Del Bo, L. Vercelloni, M. Amadori, I.L. Archetti, M. Zanotti. - In: ARCHIV FUR TIERZUCHT. - ISSN 0003-9438. - 42:Special issue(1999), pp. 100-102. ((Intervento presentato al 1. convegno International symposium on candidate genes for animal health tenutosi a Rostock nel 1999.
BoLA DRB3 exon2 polymorphism in tuberculosis infected cattle
M. LongeriPrimo
;M. ZanottiUltimo
1999
Abstract
To study the effect of BoLA-D antigens on tuberculosis (TB) progression, Italian Friesian cattle in 4 TB positive farms were sampled. In each farm 50% of sampled animals were negative and the last 50% of sampled animals were positive to TB. The -interferon test (IFN) has been used for diagnosis of TB. BoLA DRB3 exon 2 polymorphism has been performed by PCR/RFLP. The effect of DRB3.2 alleles on TB has been estimate by multiple regression models. No significant genetic effect on -IFN secretion has been recorded.
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