Neural stem cell (NSCs) are self-renewing, multipotent cells able to generate neurons, astrocytes and oligodendrocytes. Since their identification, these properties have made NSCs an attractive subject for therapeutic applications to the damaged brain. In this context, understanding the mechanisms and the molecules regulating their biological properties is important and it is focused to gain control over their proliferative and differentiative potential. Here we will discuss values and unsolved aspects of the system and the employment of potentially key molecular targets for proper control of NSCs fate.
Neural stem and progenitor cells: choosing the right Shc / T. Cataudella, L. Conti, E. Cattaneo. - 146(2004), pp. 127-133.
Titolo: | Neural stem and progenitor cells: choosing the right Shc |
Autori: | CONTI, LUCIANO (Secondo) CATTANEO, ELENA (Ultimo) |
Parole Chiave: | Animals ; Shc Signaling Adaptor Proteins ; Neuroglia ; Adaptor Proteins, Signal Transducing ; Neurons ; Humans ; Brain ; Cell Differentiation ; Stem Cells ; Neuronal Plasticity ; Adaptor Proteins, Vesicular Transport ; Cell Division |
Settore Scientifico Disciplinare: | Settore BIO/14 - Farmacologia |
Data di pubblicazione: | 2004 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/S0079-6123(03)46009-3 |
Appare nelle tipologie: | 01 - Articolo su periodico |
File in questo prodotto:
File | Descrizione | Tipologia | Licenza | |
---|---|---|---|---|
18 Cataudella ProgrBrainRes 2004.pdf | Post-print, accepted manuscript ecc. (versione accettata dall'editore) | Open Access Visualizza/Apri |