An efficient and versatile protocol for the synthesis of novel 3,7-diaryl-substituted 1,4-dihydro[1,2,4]triazolo[5,1-c][1,2,4]triazines is described, via alkylation/cyclization of 3,5-dibromo-1H-1,2,4-triazole, followed by Suzuki coupling with arylboronic acids.
Efficient Synthesis of 3,7-Diaryl-1,4-dihydro[1,2,4]triazolo[5,1-c][1,2,4]triazines / T. Sachin Aiwale, S. Dallavalle. - In: SYNTHESIS. - ISSN 0039-7881. - 44:19(2012 Oct), pp. 3055-3058. [10.1055/s-0032-1317021]
Efficient Synthesis of 3,7-Diaryl-1,4-dihydro[1,2,4]triazolo[5,1-c][1,2,4]triazines
S. Dallavalle
2012
Abstract
An efficient and versatile protocol for the synthesis of novel 3,7-diaryl-substituted 1,4-dihydro[1,2,4]triazolo[5,1-c][1,2,4]triazines is described, via alkylation/cyclization of 3,5-dibromo-1H-1,2,4-triazole, followed by Suzuki coupling with arylboronic acids.
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