A review. Both essential and toxic elements are present in the biosphere in different inorg. and organo-metallic forms. Some trace elements like Cr, Cu, Mn, Rb, Se, Tl, V, Zn are essential to human life and are present in human tissues, body fluids, cells and sub-cellular components, bonded to enzymes, proteins, etc. Many trace elements are introduced daily in the body in amounts. ranging from ng to μg per kg. A powerful tool to set up analytical procedures, to evaluate the chemical separation yield and to follow the fate of different chemical forms of ultra-trace elements on living organisms is the use of high specific activity' radioactive tracers (RT). Amongst the more effective RTs for radio-analytical chemistry, there are short-lived medium γ-energy emitters. A review of the last 25 yr in the field of both cyclotron and nuclear reactors producing high specific activity radionuclides in radio-analytical chemistry is presented. As, Au, Cu, Ga, Mn, Np, Pd, Pt, Rb, Rh, Sb, Te, Ti, Tl, V, etc., γ- and β-emitting RTs have had interesting applications in the ultra-trace metallo-toxicological field. High-resoln. γ-spectrometry by HPGe detection and β spectrometry by liq. scintillation counting, have been used, hyphenated with elemental analytical, radio-analytical and analytical techniques. The high specific activity of the no carrier added RTs is the key factor of this powerful radio analytical technique.

High Specific Activity radioactive tracers: a powerful tool for studying Low Level and Long Term Exposure to different chemical forms of both essential and toxic elements / M. Bonardi, F. Groppi, H.S. Mainardi. - In: MICROCHEMICAL JOURNAL. - ISSN 0026-265X. - 73:1,2(2002), pp. 153-166. [10.1016/S0026-265X(02)00060-7]

High Specific Activity radioactive tracers: a powerful tool for studying Low Level and Long Term Exposure to different chemical forms of both essential and toxic elements

M. Bonardi
Primo
;
F. Groppi
Secondo
;
H.S. Mainardi
Ultimo
2002

Abstract

A review. Both essential and toxic elements are present in the biosphere in different inorg. and organo-metallic forms. Some trace elements like Cr, Cu, Mn, Rb, Se, Tl, V, Zn are essential to human life and are present in human tissues, body fluids, cells and sub-cellular components, bonded to enzymes, proteins, etc. Many trace elements are introduced daily in the body in amounts. ranging from ng to μg per kg. A powerful tool to set up analytical procedures, to evaluate the chemical separation yield and to follow the fate of different chemical forms of ultra-trace elements on living organisms is the use of high specific activity' radioactive tracers (RT). Amongst the more effective RTs for radio-analytical chemistry, there are short-lived medium γ-energy emitters. A review of the last 25 yr in the field of both cyclotron and nuclear reactors producing high specific activity radionuclides in radio-analytical chemistry is presented. As, Au, Cu, Ga, Mn, Np, Pd, Pt, Rb, Rh, Sb, Te, Ti, Tl, V, etc., γ- and β-emitting RTs have had interesting applications in the ultra-trace metallo-toxicological field. High-resoln. γ-spectrometry by HPGe detection and β spectrometry by liq. scintillation counting, have been used, hyphenated with elemental analytical, radio-analytical and analytical techniques. The high specific activity of the no carrier added RTs is the key factor of this powerful radio analytical technique.
Cyclotron; High specific activity; No Carrier Added; Radio-tracers; Toxicology
Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin)
Settore CHIM/03 - Chimica Generale e Inorganica
2002
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/201633
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