In order to compare the effects on gallstone dissolution of three different doses of UDCA (4, 8 and 12 mg/kg/day), a controlled trial was carried out with seventy-one patients. The dissolution rate was higher in the group treated with the highest dose. Stone size was the major factor affecting the outcome of treatment, with a significantly higher success rate in patients with gallstones less than 10 mm than with stones greater than 10 mm.
|Titolo:||Gallstone dissolution after 6 months of ursodeoxycholic acid (UDCA): effectiveness of different doses|
PODDA, MAURO (Primo)
ZUIN, MASSIMO (Secondo)
|Parole Chiave:||Cholelithiasis; Dose-Response Relationship, Drug; Humans; Aged; Cholesterol; Ursodeoxycholic Acid; Bile; Adult; Deoxycholic Acid; Middle Aged; Time Factors; Female; Male|
|Settore Scientifico Disciplinare:||Settore MED/09 - Medicina Interna|
|Data di pubblicazione:||1982|
|Appare nelle tipologie:||01 - Articolo su periodico|