Two patients were referred because of oligospermia and azospermia, respectively. Karyotypic analysis revealed two mosaic-YY males carrying asymmetric Y chromosomes. To our knowledge, no instance of double unequal Y chromosomes has been reported so far in human males. Results of fluorescent in situ hybridization (FISH) studies in spermatozoa from one of these patients revealed a significantly high number of hyperaploid spermatozoa.
Two mosaic-YY males carrying asymmetric Y chromosomes / L. Zelante, B. Dallapiccola, S. Calvano, E. Memeo, P. Gasparini, P. Simi, S. Rossi, P. Finelli, M. Rocchi, N. Archidiacono. - In: CLINICAL GENETICS. - ISSN 0009-9163. - 51:1(1997 Jan), pp. 65-68.
Two mosaic-YY males carrying asymmetric Y chromosomes
P. Finelli;
1997
Abstract
Two patients were referred because of oligospermia and azospermia, respectively. Karyotypic analysis revealed two mosaic-YY males carrying asymmetric Y chromosomes. To our knowledge, no instance of double unequal Y chromosomes has been reported so far in human males. Results of fluorescent in situ hybridization (FISH) studies in spermatozoa from one of these patients revealed a significantly high number of hyperaploid spermatozoa.
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