The result of vitamin E treatment in 19 uremic patients in chronic hemodialysis is evaluated. In particular, the levels of erythrocyte malonyldialdehyde (MDA) and vitamin E were determined, and the fatty acid composition of red blood cell (RBC) membrane before and after treatment with parenterally administered vitamin E. A decrease of RBC MDA levels, an increase of RBC vitamin E concentrations, and a decreased saturated fatty acid to unsaturated fatty acid ratio were found after treatment with vitamin E. There was a statistically significant increase of the packed RBC volume.
Effects of alpha-tocopherol administration on red blood cell membrane lipid peroxidation in hemodialysis patients / O. Giardini, M. Taccone-Gallucci, R. Lubrano, G. Ricciardi-Tenore, D. Bandino, I. Silvi, C. Paradisi, O. Mannarino, G. Citti, M. Elli. - In: CLINICAL NEPHROLOGY. - ISSN 0301-0430. - 21:3(1984 Mar), pp. 174-7-177.
Effects of alpha-tocopherol administration on red blood cell membrane lipid peroxidation in hemodialysis patients
M. ElliUltimo
1984
Abstract
The result of vitamin E treatment in 19 uremic patients in chronic hemodialysis is evaluated. In particular, the levels of erythrocyte malonyldialdehyde (MDA) and vitamin E were determined, and the fatty acid composition of red blood cell (RBC) membrane before and after treatment with parenterally administered vitamin E. A decrease of RBC MDA levels, an increase of RBC vitamin E concentrations, and a decreased saturated fatty acid to unsaturated fatty acid ratio were found after treatment with vitamin E. There was a statistically significant increase of the packed RBC volume.
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