Pre dialysis concentrations of malonyldialdehyde (MDA) in the red blood cell membranes and pre and post dialysis percent variation of plasma haemoglobin levels are studied in a group of uraemic patients on maintenance haemodialysis both before and after a therapeutic trial with vitamin E. The findings show a significant correlation between MDA levels and percent variation of plasma haemoglobin during dialysis, thus indicating that reducing the amount of lipid peroxidation can help to reduce intradialytic chronic haemolysis.

Red blood cell membrane lipid peroxidation and chronic haemolysis in haemodialysis patients / M. Taccone-Gallucci, R. Lubrano, V. Mazzarella, D. Bandino, C. Meloni, M. Morosetti, M. Elli, O. Giardini, V. Boffo, C. Tozzo. - In: LIFE SUPPORT SYSTEMS. - ISSN 0261-989X. - 3 Suppl 1(1985), pp. 41-4-44.

Red blood cell membrane lipid peroxidation and chronic haemolysis in haemodialysis patients

M. Elli;
1985

Abstract

Pre dialysis concentrations of malonyldialdehyde (MDA) in the red blood cell membranes and pre and post dialysis percent variation of plasma haemoglobin levels are studied in a group of uraemic patients on maintenance haemodialysis both before and after a therapeutic trial with vitamin E. The findings show a significant correlation between MDA levels and percent variation of plasma haemoglobin during dialysis, thus indicating that reducing the amount of lipid peroxidation can help to reduce intradialytic chronic haemolysis.
Humans; Aged; Child; Renal Dialysis; Lipid Peroxides; Vitamin E; Membrane Lipids; Uremia; Adult; Hemolysis; Middle Aged; Adolescent; Erythrocyte Membrane; Female; Male; Malondialdehyde
Settore MED/18 - Chirurgia Generale
Settore MED/14 - Nefrologia
LIFE SUPPORT SYSTEMS
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/191581
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