The chiral complexes [Pd(eta-3-allyl)(P-P')]X [P-P' = the chiral chelating ligand (S)(N-diphenylphosphino) (2-diphenylphosphinoxymethyl)pyrrolidine; allyl = MeCHCHCHMe, 2; or PhCHCHCHPh 3; X = BF4- or PF6-] have been prepared and analysed by NMR spectroscopy. Their diastereoisomeric composition have been determined on the basis of H-1, C-13, P-31 and two-dimensional H-1-X (X = C-13 or P-31) correlation NMR spectra. Since retention of the preferred syn disposition of the allylic substituents occurs in both cases the reaction product is a mixture of two isomers which differ in allylic chirality. The relative absolute configurations have been assigned by two-dimensional nuclear Overhauser effect measurements and confirmed by the X-ray crystallographic determination of the structure of the major diastereoisomer of 2: the allyl fragments have (1S,3R) absolute configuration. The reaction of racemic 1,3-dimethylprop-2-enyl acetate in the presence of 2 and of 1,3-diphenylprop-2-enyl acetate in the presence of 3 with sodium dimethyl malonate gives the allylic alkylation products in 20 and 30% enantiomeric excess respectively.
Nuclear magnetic resonance and crystallographic studies of chiral h3-allyl palladium(II) complexes and asymmetric allylic alkylation of propen-2-yl acetates / E. Cesarotti, M. Grassi, L. Prati, F. Demartin. - In: JOURNAL OF THE CHEMICAL SOCIETY DALTON TRANSACTIONS. - ISSN 0300-9246. - 1991:8(1991), pp. 2073-2082.
|Titolo:||Nuclear magnetic resonance and crystallographic studies of chiral h3-allyl palladium(II) complexes and asymmetric allylic alkylation of propen-2-yl acetates|
|Parole Chiave:||NMR-spectroscopy; catalytic allylation; platiunum complexes; phosphine-ligands; hydrogenation; mechanism; behavior|
|Settore Scientifico Disciplinare:||Settore CHIM/03 - Chimica Generale e Inorganica|
|Data di pubblicazione:||1991|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1039/dt9910002073|
|Appare nelle tipologie:||01 - Articolo su periodico|