Nitrogen balance, insulin and C peptide profiles were evaluated in 24 normo metabolic malnourishedpatients during parenteral feeding with three different diets. The nitrogen source and amount were identical (0.22 g/kg/day) but the calorie supply was different: 35 and 50 kcal as glucose or 50 kcal in a mixedsystem (15 kcal lipid). There were three groups: low (L) and high (H) glucose (G) and H lipid (L). Nitrogen balance in HG subset was higher than HL (0.019 ± 0.012 vs −0.022 ± 0.07, SEM, p < 0.001). The latter did not show any difference with respect to LG (0.006 ± 0.011). Insulin and C peptide plasma levels (limited to H groups) decreased during the study after an early peak; this decrease was significantly related to time in both groups and was significantly higher for both hormones in the HG group. However insulin plasma levels were always higher in the HG group and the better nitrogen balance in this group may be related to the anabolic activity of insulin.
|Titolo:||A comparison of mixed and glucose systems in the total parenteral nutrition of malnourished patients|
IAPICHINO, GAETANO (Primo)
|Settore Scientifico Disciplinare:||Settore MED/41 - Anestesiologia|
|Data di pubblicazione:||feb-1987|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/0261-5614(87)90060-4|
|Appare nelle tipologie:||01 - Articolo su periodico|