Nitrogen balance, insulin and C peptide profiles were evaluated in 24 normo metabolic malnourishedpatients during parenteral feeding with three different diets. The nitrogen source and amount were identical (0.22 g/kg/day) but the calorie supply was different: 35 and 50 kcal as glucose or 50 kcal in a mixedsystem (15 kcal lipid). There were three groups: low (L) and high (H) glucose (G) and H lipid (L). Nitrogen balance in HG subset was higher than HL (0.019 ± 0.012 vs −0.022 ± 0.07, SEM, p < 0.001). The latter did not show any difference with respect to LG (0.006 ± 0.011). Insulin and C peptide plasma levels (limited to H groups) decreased during the study after an early peak; this decrease was significantly related to time in both groups and was significantly higher for both hormones in the HG group. However insulin plasma levels were always higher in the HG group and the better nitrogen balance in this group may be related to the anabolic activity of insulin.

A comparison of mixed and glucose systems in the total parenteral nutrition of malnourished patients / G. Iapichino, D. Radrizzani, L. Leoni, G. Osti, A. Scherini, A. Colombo, G. Ronzoni. - In: CLINICAL NUTRITION. - ISSN 0261-5614. - 6:1(1987 Feb), pp. 1-4.

A comparison of mixed and glucose systems in the total parenteral nutrition of malnourished patients

G. Iapichino
Primo
;
1987

Abstract

Nitrogen balance, insulin and C peptide profiles were evaluated in 24 normo metabolic malnourishedpatients during parenteral feeding with three different diets. The nitrogen source and amount were identical (0.22 g/kg/day) but the calorie supply was different: 35 and 50 kcal as glucose or 50 kcal in a mixedsystem (15 kcal lipid). There were three groups: low (L) and high (H) glucose (G) and H lipid (L). Nitrogen balance in HG subset was higher than HL (0.019 ± 0.012 vs −0.022 ± 0.07, SEM, p < 0.001). The latter did not show any difference with respect to LG (0.006 ± 0.011). Insulin and C peptide plasma levels (limited to H groups) decreased during the study after an early peak; this decrease was significantly related to time in both groups and was significantly higher for both hormones in the HG group. However insulin plasma levels were always higher in the HG group and the better nitrogen balance in this group may be related to the anabolic activity of insulin.
Settore MED/41 - Anestesiologia
Article (author)
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/184920
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 3
  • ???jsp.display-item.citation.isi??? 2
social impact