A concd. soln. (drop formulation) of nifedipine (I) [21829-25-4] was dild. 50-fold (for clin. use) with H2O, exposed for 1-10 min to normal lab illumination, and analyzed for degrdn. products by HPLC. More than 95% of I was still intact after 10 min, a time sufficient for normal diln. The relative std. deviation for the HPLC method was 2.78%.
|Titolo:||Study of the light stability of nifedipine in a drop formulation under therapeutic use conditions|
|Settore Scientifico Disciplinare:||Settore CHIM/08 - Chimica Farmaceutica|
|Data di pubblicazione:||1985|
|Appare nelle tipologie:||01 - Articolo su periodico|