In vitro reaction of 17-OH tabersonine 2a and its 11-OMe analogue 2b with adenine, tri-O-acetyl adenosine, -guanosine and -cytidine under mild conditions, results in covalent adducts by electrophilic attack of reactive C-17 position of the alkaloids on the exocyclic nitrogen.

COVALENT NUCLEOSIDE ADDUCTS OF ASPIDOSPERMA ALKALOIDS / B. DANIELI, G. LESMA, G. PALMISANO, D. PASSARELLA, B. PYUSKYULEV. - In: NUCLEOSIDES & NUCLEOTIDES. - ISSN 0732-8311. - 10:8(1991), pp. 1667-1675.

COVALENT NUCLEOSIDE ADDUCTS OF ASPIDOSPERMA ALKALOIDS

B. DANIELI
Primo
;
G. LESMA
Secondo
;
D. PASSARELLA
Penultimo
;
1991

Abstract

In vitro reaction of 17-OH tabersonine 2a and its 11-OMe analogue 2b with adenine, tri-O-acetyl adenosine, -guanosine and -cytidine under mild conditions, results in covalent adducts by electrophilic attack of reactive C-17 position of the alkaloids on the exocyclic nitrogen.
Settore CHIM/06 - Chimica Organica
1991
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/183697
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