The convergent synthesis of the iso-Leukotriene B4 (XVI) (as diastereoisomeric mixture with the desired geometry), by Wittig's condensation of the two precursor synthons at 6 (VI) and 14 C (XIV), starting from the common cyclic acrylaldehyde dimer (I), is reported.
A route to the total synthesis of iso-LTB4 system / D. Pirillo, A. Gazzaniga, P. Leggeri, P. Giaccone, G. Traverso. - In: IL FARMACO. EDIZIONE SCIENTIFICA. - ISSN 0430-0920. - 40:4(1985 Apr), pp. 249-252.
A route to the total synthesis of iso-LTB4 system
A. GazzanigaSecondo
;
1985-04
Abstract
The convergent synthesis of the iso-Leukotriene B4 (XVI) (as diastereoisomeric mixture with the desired geometry), by Wittig's condensation of the two precursor synthons at 6 (VI) and 14 C (XIV), starting from the common cyclic acrylaldehyde dimer (I), is reported.
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