The convergent synthesis of the iso-Leukotriene B4 (XVI) (as diastereoisomeric mixture with the desired geometry), by Wittig's condensation of the two precursor synthons at 6 (VI) and 14 C (XIV), starting from the common cyclic acrylaldehyde dimer (I), is reported.

A route to the total synthesis of iso-LTB4 system / D. Pirillo, A. Gazzaniga, P. Leggeri, P. Giaccone, G. Traverso. - In: IL FARMACO. EDIZIONE SCIENTIFICA. - ISSN 0430-0920. - 40:4(1985 Apr), pp. 249-252.

A route to the total synthesis of iso-LTB4 system

A. Gazzaniga
Secondo
;
1985-04

Abstract

The convergent synthesis of the iso-Leukotriene B4 (XVI) (as diastereoisomeric mixture with the desired geometry), by Wittig's condensation of the two precursor synthons at 6 (VI) and 14 C (XIV), starting from the common cyclic acrylaldehyde dimer (I), is reported.
Stereoisomerism; Leukotriene B4; Chemistry; Chemical Phenomena; Chromatography, High Pressure Liquid
Settore CHIM/09 - Farmaceutico Tecnologico Applicativo
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/181672
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