The binding capacities of {amalgamation}-cyclodextrin samples containing different amounts of water have been investigated. Crushing strength of tablets obtained with a single-punch tableting machine was used as a measure of the cohesive properties of powders. The results clearly indicate a determinant role of adsorbed water on powder compactability. The effect of aging is also stressed and discussed.
The influence of water content on the binding capacity of β-cyclodextrin / F. Giordano, A. Gazzaniga, G. Bettinetti, A. La Manna. - In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. - ISSN 0378-5173. - 62:2-3(1990), pp. 153-156.
The influence of water content on the binding capacity of β-cyclodextrin
A. GazzanigaSecondo
;
1990
Abstract
The binding capacities of {amalgamation}-cyclodextrin samples containing different amounts of water have been investigated. Crushing strength of tablets obtained with a single-punch tableting machine was used as a measure of the cohesive properties of powders. The results clearly indicate a determinant role of adsorbed water on powder compactability. The effect of aging is also stressed and discussed.
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