The authors studied the behaviour of cyclic 3',5' AMP phosphodiesterase in the 2,000 g supernatant of the F. hepatica homogenate, under basal conditions and after addition of various substances. Dopamine markedly inhibits the enzyme activity, imidazole causes a strong activation, while serotonin, theophylline, PGE1, and PGF(2α) appear to be ineffective.
Cyclic AMP phosphodiesterase activity in Fasciola hepatica / T. Simonic, P. Sartorelli, A. Locatelli. - In: ANNALES DE PARASITOLOGIE HUMAINE ET COMPAREE. - ISSN 0003-4150. - 50:4(1975), pp. 461-468.
Cyclic AMP phosphodiesterase activity in Fasciola hepatica
T. SimonicPrimo
;P. SartorelliSecondo
;
1975
Abstract
The authors studied the behaviour of cyclic 3',5' AMP phosphodiesterase in the 2,000 g supernatant of the F. hepatica homogenate, under basal conditions and after addition of various substances. Dopamine markedly inhibits the enzyme activity, imidazole causes a strong activation, while serotonin, theophylline, PGE1, and PGF(2α) appear to be ineffective.
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