The intramolecular Friedel-Crafts reaction of indole-2-carboxylic acid β-oxoamides catalyzed by trifluoroacetic acid or InCl3, is a convenient method for the synthesis of 3-aryl-, 4-aryl-, and 4-alkyl-β-carbolin-1-ones.
Intramolecular friedel-crafts reaction of indoles with carbonyl groups: a simple synthesis of 3- and 4-substituted β-carbolin-1-ones / R. Cincinelli, S. Dallavalle, L. Merlini. - In: SYNLETT. - ISSN 0936-5214. - 9:9(2008), pp. 1309-1312. [10.1055/s-2008-1072613]
Intramolecular friedel-crafts reaction of indoles with carbonyl groups: a simple synthesis of 3- and 4-substituted β-carbolin-1-ones
R. CincinelliPrimo
;S. DallavalleSecondo
;L. MerliniUltimo
2008
Abstract
The intramolecular Friedel-Crafts reaction of indole-2-carboxylic acid β-oxoamides catalyzed by trifluoroacetic acid or InCl3, is a convenient method for the synthesis of 3-aryl-, 4-aryl-, and 4-alkyl-β-carbolin-1-ones.File in questo prodotto:
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