Benzylalkyl sulfides with alkyl groups from methyl to hexyl, para-alkylbenzyl groups from methyl to butyl, 2-phenylethyl methyl sulfide and 3-phenylpropyl methyl sulfide have been oxidized by cyclohexanonemonooxygenase from AcinetobacterNCIB9871. Sulfoxides with enantiomeric excesses ranging from 80% for the (R)-configuration to 96% ee for the (S)-configuration were obtained. Cyclohexanonemonooxygenase (CMO) catalyzed the asymmetric oxidation of numerous benzylalkyl sulfides to sulfoxides with ee up to 96%.
|Titolo:||Synthesis of chiral benzyl alkyl sulfoxides by cyclohexanone Monooxygenase from Acinetobacter NCIB 9871|
DALLAVALLE, SABRINA (Ultimo)
|Settore Scientifico Disciplinare:||Settore CHIM/06 - Chimica Organica|
|Data di pubblicazione:||1995|
|Digital Object Identifier (DOI):||10.1016/0957-4166(95)00102-U|
|Appare nelle tipologie:||01 - Articolo su periodico|