We evaluated retrospectively the efficacy and tolerability of oral albendazole (400 mg/day for 1 week) in 78 patients with hookworm-related cutaneous larva migrans characterized by multiple and/or extensive lesions. The diagnosis was based on history and the clinical picture. Neither topical or systemic drugs nor physical treatments were used. All patients were followed-up for at least 3 months after the therapy. All patients were cured at the end of the therapy. The disappearance of pruritus was reported after 2-3 days and skin lesions after 5-7 days of therapy. One patient reported nausea and abdominal pain; another patient reported worsening of pruritus: in both cases it was not necessary to stop the therapy. No recurrences were observed during follow-up. One week of therapy with 400 mg/day oral albendazole is very effective (cure rate: 100%) in patients with cutaneous larva migrans characterized by multiple and/or extensive lesions. This therapeutical regimen is not accompanied by the appearance of new and/or more severe side effects.
One-week therapy with oral albendazole in hookworm-related cutaneous larva migrans : a retrospective study on 78 patients / S. Veraldi, S. Bottini, G. Rizzitelli, M.C. Persico. - In: THE JOURNAL OF DERMATOLOGICAL TREATMENT. - ISSN 0954-6634. - 23:3(2012 Jun), pp. 189-191.
|Titolo:||One-week therapy with oral albendazole in hookworm-related cutaneous larva migrans : a retrospective study on 78 patients|
VERALDI, STEFANO (Primo)
|Parole Chiave:||Albendazole; Hookworm-related cutaneous larva migrans|
|Settore Scientifico Disciplinare:||Settore MED/35 - Malattie Cutanee e Veneree|
Settore MED/17 - Malattie Infettive
|Data di pubblicazione:||giu-2012|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.3109/09546634.2010.544707|
|Appare nelle tipologie:||01 - Articolo su periodico|