Metabolic adaptation is a key component of macrophage plasticity and polarization, instrumental to their function in homeostasis, immunity, and inflammation. Macrophage products also impact metabolism, as illustrated by obesity-associated pathologies. Defining the mechanisms regulating macrophage metabolic activity and orchestration of metabolism by macrophages is crucial to pathology and therapeutic intervention.
Orchestration of metabolism by macrophages / S.K. Biswas, A. Mantovani. - In: CELL METABOLISM. - ISSN 1550-4131. - 15:4(2012 Apr 04), pp. 432-437.
Orchestration of metabolism by macrophages
A. MantovaniUltimo
2012
Abstract
Metabolic adaptation is a key component of macrophage plasticity and polarization, instrumental to their function in homeostasis, immunity, and inflammation. Macrophage products also impact metabolism, as illustrated by obesity-associated pathologies. Defining the mechanisms regulating macrophage metabolic activity and orchestration of metabolism by macrophages is crucial to pathology and therapeutic intervention.
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