Chiral beta-sulfonopeptides were synthesized both in solution and in the solid phase using the sulfonyl chlorides derived from enantiomerically pure 2-substituted taurines under mild coupling conditions [cat. 4-dimethylaminopyridine (DMAP) and excess methyl trimethylsilyl dimethylketene acetal (MTDA) as a proton trap]. Copyright (C) 1996 Elsevier Science Ltd
A new method for the solution and solid phase synthesis of chiral beta-sulfonopeptides under mild conditions / M. Gude, U. Piarulli, D. Potenza, B. Salom, C.M.A. Gennari. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 37:47(1996), pp. 8589-8592.
A new method for the solution and solid phase synthesis of chiral beta-sulfonopeptides under mild conditions
D. Potenza;C.M.A. GennariUltimo
1996
Abstract
Chiral beta-sulfonopeptides were synthesized both in solution and in the solid phase using the sulfonyl chlorides derived from enantiomerically pure 2-substituted taurines under mild coupling conditions [cat. 4-dimethylaminopyridine (DMAP) and excess methyl trimethylsilyl dimethylketene acetal (MTDA) as a proton trap]. Copyright (C) 1996 Elsevier Science Ltd
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