The title compound (2), a prenylogue of mycophenolic acid (4), has been synthesized by two different routes; experiments show unambiguously that (2) is a biosynthetic intermediate of mycophenolic acid.
(E,E)-10-(1,3-Dihydro-4,6-dihydroxy-7-methyl-3-oxoisobenzofuran-5-yl)4, 8-dimethyldeca-4,8-dienoic acid: Total synthesis and role in mycophenolic acid biosynthesis / L. Colombo, C.M.A. Gennari, D. Potenza, C. Scolastico, F. Aragozzini. - In: JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS. - ISSN 0022-4936. - :22(1979), pp. 1021-1022. [10.1039/C39790001021]
(E,E)-10-(1,3-Dihydro-4,6-dihydroxy-7-methyl-3-oxoisobenzofuran-5-yl)4, 8-dimethyldeca-4,8-dienoic acid: Total synthesis and role in mycophenolic acid biosynthesis
C.M.A. Gennari;D. Potenza;C. Scolastico;
1979
Abstract
The title compound (2), a prenylogue of mycophenolic acid (4), has been synthesized by two different routes; experiments show unambiguously that (2) is a biosynthetic intermediate of mycophenolic acid.
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