Background:Adiposity may contribute to the future risk of disease. The aim was to evaluate the accuracy and reliability of an air-displacement plethysmography system (ADP) to estimate percentage fat mass (%FM) in preterm infants and to evaluate inter-device reliability in infants.Methods:70 preterm and 9 full term infants were assessed. The accuracy of ADP measurements was assessed by determining reference %FM values using H(2)(18)O dilution measurement.Results:Mean %FM by ADP was 5.67 ± 1.84 and mean % FM by H(2)(18)O dilution was 5.99 ± 2.56. Regression analysis showed that % FM by ADP was associated with %FM by H(2)(18)O dilution (R(2)=0.63,standard error of estimate (SEE)=1.65, P=0.006). Bland-Altman analysis showed no bias (r=-0.48, P=0.16) and 95% limits of agreement were -3.40 to 2.76 %FM. There was no difference in mean inter-device reliability %FM values (8.97 vs. 8.55 %FM) between ADP 1 and 2. Regression analysis indicated a low SEE (1.14% FM), high R(2) (0.91) and 95% limits of agreement were -1.87 to 2.71% FM. The regression line also did not differ significantly from the line of identity.Conclusion:ADP is a noninvasive, reliable, and accurate technique to measure preterm infants' body composition in both research and clinical settings.

Evaluation of air-displacement plethysmography for body composition assessment in preterm infants / P. Roggero, M.L. Giannì, O. Amato, P. Piemontese, D. Morniroli, W.W. Wong, F. Mosca. - In: PEDIATRIC RESEARCH. - ISSN 0031-3998. - 72:3(2012 Sep), pp. 316-320. [10.1038/pr.2012.75]

Evaluation of air-displacement plethysmography for body composition assessment in preterm infants

M.L. Giannì
Secondo
;
O. Amato;D. Morniroli;F. Mosca
Ultimo
2012-09

Abstract

Background:Adiposity may contribute to the future risk of disease. The aim was to evaluate the accuracy and reliability of an air-displacement plethysmography system (ADP) to estimate percentage fat mass (%FM) in preterm infants and to evaluate inter-device reliability in infants.Methods:70 preterm and 9 full term infants were assessed. The accuracy of ADP measurements was assessed by determining reference %FM values using H(2)(18)O dilution measurement.Results:Mean %FM by ADP was 5.67 ± 1.84 and mean % FM by H(2)(18)O dilution was 5.99 ± 2.56. Regression analysis showed that % FM by ADP was associated with %FM by H(2)(18)O dilution (R(2)=0.63,standard error of estimate (SEE)=1.65, P=0.006). Bland-Altman analysis showed no bias (r=-0.48, P=0.16) and 95% limits of agreement were -3.40 to 2.76 %FM. There was no difference in mean inter-device reliability %FM values (8.97 vs. 8.55 %FM) between ADP 1 and 2. Regression analysis indicated a low SEE (1.14% FM), high R(2) (0.91) and 95% limits of agreement were -1.87 to 2.71% FM. The regression line also did not differ significantly from the line of identity.Conclusion:ADP is a noninvasive, reliable, and accurate technique to measure preterm infants' body composition in both research and clinical settings.
Settore MED/38 - Pediatria Generale e Specialistica
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/175632
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