The chosen one: The desymmetrization of meso-2 is possible with the use of diethylzinc in the presence of the Cu' complex of 1 (10 mol%; Tf = CF3SO2). Ligand 1 was optimized from a screen of a library of 125 compounds. Other ligands from the same library favor the formation of the opposite enantiomer 4.

A catalytic and enantioselective desymmetrization of meso cyclic allylic bisdiethylphosphates with organozinc reagents / U. Piarulli, P.G.S. Daubos, C. Claverie, M. Roux, C.M.A. Gennari. - In: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION. - ISSN 1433-7851. - 42:2(2003), pp. 234-236.

A catalytic and enantioselective desymmetrization of meso cyclic allylic bisdiethylphosphates with organozinc reagents

P.G.S. Daubos
Secondo
;
C.M.A. Gennari
Ultimo
2003

Abstract

The chosen one: The desymmetrization of meso-2 is possible with the use of diethylzinc in the presence of the Cu' complex of 1 (10 mol%; Tf = CF3SO2). Ligand 1 was optimized from a screen of a library of 125 compounds. Other ligands from the same library favor the formation of the opposite enantiomer 4.
alkylation ; asymmetric synthesis ; copper ; organophosphates ; zinc
Settore CHIM/06 - Chimica Organica
Article (author)
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/175261
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 72
  • ???jsp.display-item.citation.isi??? 61
social impact