This paper describes the successful transfer of benzotriazole-based chemistry on solid support. The strategy followed to anchor this peculiar heterocycle on solid phase and the full analytical characterization of the various supported benzotriazoles are herein described. The chemistry assessment process on solid phase, the preparation of discrete libraries by parallel synthesis, the semiautomated purification procedures, and the complete analytical characterization of the library components are also presented and discussed.

Solid-Supported Benzotriazoles: Synthetic Auxiliaries and Traceless Linkers for the Combinatorial Synthesis of Amine Libraries / A. Paio, A. Zaramella, R. Ferritto, N. Conti, C. Marchioro, P. Seneci. - In: JOURNAL OF COMBINATORIAL CHEMISTRY. - ISSN 1520-4766. - 1:4(1999), pp. 317-325.

Solid-Supported Benzotriazoles: Synthetic Auxiliaries and Traceless Linkers for the Combinatorial Synthesis of Amine Libraries

P. Seneci
Ultimo
1999

Abstract

This paper describes the successful transfer of benzotriazole-based chemistry on solid support. The strategy followed to anchor this peculiar heterocycle on solid phase and the full analytical characterization of the various supported benzotriazoles are herein described. The chemistry assessment process on solid phase, the preparation of discrete libraries by parallel synthesis, the semiautomated purification procedures, and the complete analytical characterization of the library components are also presented and discussed.
Settore CHIM/06 - Chimica Organica
1999
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/170562
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