A number of analogues of the recently described compound nematophin were prepared and studied for antibacterial activity. The 2-phenyl derivative was found to exhibit exceptional activity against methicillin resistant Staphylococcus aureus (MRSA) whereas the isosteric benzimidazole analogue was much less active.
Studies on the novel anti-staphyloccal compound nematophin / G. Kennedy, M. Viziano, J.A. Winders, P. Cavallini, M. Gevi, F. Micheli, P. Rodegher, P. Seneci, A. Zumerle. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - 10:15(2000 Aug 07), pp. 1751-1754. [10.1016/S0960-894X(00)00331-0]
Studies on the novel anti-staphyloccal compound nematophin
P. SeneciPenultimo
;
2000
Abstract
A number of analogues of the recently described compound nematophin were prepared and studied for antibacterial activity. The 2-phenyl derivative was found to exhibit exceptional activity against methicillin resistant Staphylococcus aureus (MRSA) whereas the isosteric benzimidazole analogue was much less active.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
