Different strategies for the discovery of novel leads interacting with therapeutically relevant targets are thoroughly presented and discussed, using also three recent examples. Emphasis is given to approaches which do not require extensive resources and budgets, but rather prove how cleverness and creativity can provide active compounds in drug discovery.
Combinatorial chemistry and high-throughput screening in drug discovery: different strategies and formats [Recensione] / P. Seneci, S. Miertus. - In: MOLECULAR DIVERSITY. - ISSN 1381-1991. - 5:2(2000), pp. 75-89.
Combinatorial chemistry and high-throughput screening in drug discovery: different strategies and formats
P. SeneciPrimo
;
2000
Abstract
Different strategies for the discovery of novel leads interacting with therapeutically relevant targets are thoroughly presented and discussed, using also three recent examples. Emphasis is given to approaches which do not require extensive resources and budgets, but rather prove how cleverness and creativity can provide active compounds in drug discovery.
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