Chemokines are important components of cancer-related inflammation. In this issue of Cancer Cell, Chen et al. report that the chemokine CCL18, produced by tumor-associated macrophages, promotes malignant behavior and correlates with metastasis in human breast cancer. Unexpectedly, PITPNM3/Nir1, a molecule unrelated to chemokine receptors, was identified as its elusive receptor.

Chemokines and cancer: a fatal attraction / R. Bonecchi, M. Locati, A. Mantovani. - In: CANCER CELL. - ISSN 1535-6108. - 19:4(2011 Apr 12), pp. 434-435. [10.1016/j.ccr.2011.03.017]

Chemokines and cancer: a fatal attraction

R. Bonecchi;M. Locati;A. Mantovani
2011-04-12

Abstract

Chemokines are important components of cancer-related inflammation. In this issue of Cancer Cell, Chen et al. report that the chemokine CCL18, produced by tumor-associated macrophages, promotes malignant behavior and correlates with metastasis in human breast cancer. Unexpectedly, PITPNM3/Nir1, a molecule unrelated to chemokine receptors, was identified as its elusive receptor.
Settore MED/04 - Patologia Generale
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/159021
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