Boron neutron capture therapy (BNCT) is a cancer radiotherapy that uses epithermal and thermal neutron beams.The determination of the absorbed dose in healthy tissue, separating the various dose contributions having different radiobiological effectiveness (RBE) is of great importance for therapy planning. However, a standard code of practice has not yet been established because suitable methods for dosimetry in BNCT are still in progress. A study about the characterization o fthe epithermal column of the LVR-15 research reactor in Rez (CZ) has been performed, in particular concerning the fast-neutron dose. This dose is no tnegligible and its determination is important owing to its high RBE. Fast-neutron and photon dose distributions in a water phantom have been measured by means of Frickegel layer dosimeters. Even if gel layer dosimetry is not yet standardized, it is presently the only method for obtaining images of each dose contribution in BNCT neutron fields. The results were compared with values measured with thermoluminescence detectors, twin ionization chambers, data taken from literature and MonteCarlo simulations.

Fast-neutron dose evaluation in BNCT with Fricke gel layer detectors / G. Gambarini, G. Bartesaghi, J. Burian, M. Carrara, M. Marek, A. Negri, L. Pirola, L. Viererbl. - In: RADIATION MEASUREMENTS. - ISSN 1350-4487. - 45:10(2010), pp. 1398-1401. [10.1016/j.radmeas.2010.05.004]

Fast-neutron dose evaluation in BNCT with Fricke gel layer detectors

G. Gambarini
Primo
;
G. Bartesaghi
Secondo
;
A. Negri;L. Pirola
Penultimo
;
2010

Abstract

Boron neutron capture therapy (BNCT) is a cancer radiotherapy that uses epithermal and thermal neutron beams.The determination of the absorbed dose in healthy tissue, separating the various dose contributions having different radiobiological effectiveness (RBE) is of great importance for therapy planning. However, a standard code of practice has not yet been established because suitable methods for dosimetry in BNCT are still in progress. A study about the characterization o fthe epithermal column of the LVR-15 research reactor in Rez (CZ) has been performed, in particular concerning the fast-neutron dose. This dose is no tnegligible and its determination is important owing to its high RBE. Fast-neutron and photon dose distributions in a water phantom have been measured by means of Frickegel layer dosimeters. Even if gel layer dosimetry is not yet standardized, it is presently the only method for obtaining images of each dose contribution in BNCT neutron fields. The results were compared with values measured with thermoluminescence detectors, twin ionization chambers, data taken from literature and MonteCarlo simulations.
BNCT; Dose imaging; Gel dosimetry; Neutron dosimetry
Settore FIS/01 - Fisica Sperimentale
Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin)
2010
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/152202
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