High prevalence of hepatitis B virus (HBV) infection in China offers a unique setting to examine HBVs influence on the presentation of dengue fever. In 398 patients admitted for suspected dengue fever, 89% (353/398) were positive for dengue IgM antibodies. Among dengue-infected patients, 8% (29/353) had chronic HBV co-infection. Only dengue virus serotype 1 was identified by virus isolation and reverse transcriptase-polymerase chain reaction assays. No case of dengue hemorrhagic fever/dengue shock syndrome was diagnosed. In addition to routine clinical tests, interleukin 2 (IL-2), IL-4, IL-6, IL-10, interferon γ (IFNγ), and tumor necrosis factor α (TNFα) levels were measured in the sera of 95% (334/353) of dengue-infected subjects as well as controls. Surprisingly, HBV/dengue co-infected patients made less IL-6 (P < 0.05) and TNFα (P < 0.05) than patients with only dengue infection. Similar levels of IL-4, IL-10, and IFNγ were found in both groups. Thus, HBV co-infection seems to alter the cytokine production pattern when patients contract dengue infection. Copyright
Evaluation of different antibodies for immunostaining of Wolbachia in Brugia Malayi and other filarial parasites / K. Fischer, G.J. Weil, C. Bandi, M.L. Michalski, J.A. Vaughan, P. Fischer. - In: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. - ISSN 0002-9637. - 79:Suppl. al n. 6(2008 Dec), pp. 154-154. ((Intervento presentato al 57. convegno Annual Meeting American Society of Tropical Medicine and Hygiene tenutosi a New Orleans nel 2008.
Evaluation of different antibodies for immunostaining of Wolbachia in Brugia Malayi and other filarial parasites
C. Bandi;
2008
Abstract
High prevalence of hepatitis B virus (HBV) infection in China offers a unique setting to examine HBVs influence on the presentation of dengue fever. In 398 patients admitted for suspected dengue fever, 89% (353/398) were positive for dengue IgM antibodies. Among dengue-infected patients, 8% (29/353) had chronic HBV co-infection. Only dengue virus serotype 1 was identified by virus isolation and reverse transcriptase-polymerase chain reaction assays. No case of dengue hemorrhagic fever/dengue shock syndrome was diagnosed. In addition to routine clinical tests, interleukin 2 (IL-2), IL-4, IL-6, IL-10, interferon γ (IFNγ), and tumor necrosis factor α (TNFα) levels were measured in the sera of 95% (334/353) of dengue-infected subjects as well as controls. Surprisingly, HBV/dengue co-infected patients made less IL-6 (P < 0.05) and TNFα (P < 0.05) than patients with only dengue infection. Similar levels of IL-4, IL-10, and IFNγ were found in both groups. Thus, HBV co-infection seems to alter the cytokine production pattern when patients contract dengue infection. CopyrightPubblicazioni consigliate
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