During the 2006-2007 season, 19 HIV-uninfected and 33 HIV-infected children and adolescents with full immunovirologic response to HAART were immunized against influenza and subsequently followed up. One month post-immunization all subjects had protective antibodies titres which persisted for the whole influenza season. Seven vaccinees (four HIV-infected and three HIV-uninfected) were found to be infected by influenza viruses during the epidemic, but disease was lab-confirmed only in two HIV-infected subjects. Both presented a benign clinical course and were infected by an A/Brisbane/10/07-H3N2-like virus. These data indicate that HIV-infected subjects benefit from routine seasonal influenza vaccination.
Influenza surveillance in a cohort of HIV-infected children and adolescents immunized against seasonal influenza / A. Amendola, E. Pariani, A. Viganò, P. Erba, A. Zappa, V. Giacomet, E. Tanzi, G.V. Zuccotti, A.R. Zanetti. - In: VACCINE. - ISSN 0264-410X. - 28:15(2010 Mar), pp. 2700-2704. [10.1016/j.vaccine.2010.01.021]
Influenza surveillance in a cohort of HIV-infected children and adolescents immunized against seasonal influenza
A. Amendola;E. Pariani;V. Giacomet;E. Tanzi;G.V. Zuccotti;A.R. Zanetti
2010
Abstract
During the 2006-2007 season, 19 HIV-uninfected and 33 HIV-infected children and adolescents with full immunovirologic response to HAART were immunized against influenza and subsequently followed up. One month post-immunization all subjects had protective antibodies titres which persisted for the whole influenza season. Seven vaccinees (four HIV-infected and three HIV-uninfected) were found to be infected by influenza viruses during the epidemic, but disease was lab-confirmed only in two HIV-infected subjects. Both presented a benign clinical course and were infected by an A/Brisbane/10/07-H3N2-like virus. These data indicate that HIV-infected subjects benefit from routine seasonal influenza vaccination.Pubblicazioni consigliate
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