Objectives - To analyse prognostic factors in patients operated upon for cerebral aneurysms. A previous investigation by our group showed that patients operated later than 10 days after bleeding have a worse neuropsychological prognosis, but the number of patients operated upon within 3 days was not sufficient. Here, a new sample of patients with early surgery is included in the analyses. Material and methods - Patients numbered 148 (65 with ACoA, 39 with MCA, and 44 with PCoA aneurysms): 56 were operated within 3 days, 44 within 4-10 days, and 48 after at least 10 days from bleeding. A standardized battery of 13 neuropsychological tests was adopted: we considered both the number of defective scores and the average performance. Results - Patients operated later than 10 days after bleeding had a worse prognosis than the 2 groups with early and intermediate surgery, which were not different. Aneurysm site was not relevant. Old age and low education were associated with a worse prognosis. Hunt and Hess scores at operation and post operation were also predictive of the outcome. Conclusion - On the whole, patients operated upon later than 10 days after bleeding have a less favourable prognosis than those with earlier operation timing.

Neuropsychological outcome of operated cerebral aneurysms : prognostic factors on 148 patients / A. De Santis, M. Laiacona, R. Barbarotto, O. De Divitiis, M. Migliore, E. Capitani. - In: ACTA NEUROLOGICA SCANDINAVICA. - ISSN 0001-6314. - 97:6(1998 Jun), pp. 393-397.

Neuropsychological outcome of operated cerebral aneurysms : prognostic factors on 148 patients

A. De Santis
Primo
;
E. Capitani
Ultimo
1998-06

Abstract

Objectives - To analyse prognostic factors in patients operated upon for cerebral aneurysms. A previous investigation by our group showed that patients operated later than 10 days after bleeding have a worse neuropsychological prognosis, but the number of patients operated upon within 3 days was not sufficient. Here, a new sample of patients with early surgery is included in the analyses. Material and methods - Patients numbered 148 (65 with ACoA, 39 with MCA, and 44 with PCoA aneurysms): 56 were operated within 3 days, 44 within 4-10 days, and 48 after at least 10 days from bleeding. A standardized battery of 13 neuropsychological tests was adopted: we considered both the number of defective scores and the average performance. Results - Patients operated later than 10 days after bleeding had a worse prognosis than the 2 groups with early and intermediate surgery, which were not different. Aneurysm site was not relevant. Old age and low education were associated with a worse prognosis. Hunt and Hess scores at operation and post operation were also predictive of the outcome. Conclusion - On the whole, patients operated upon later than 10 days after bleeding have a less favourable prognosis than those with earlier operation timing.
intracranial aneurysms ; neuropsychological outcome ; prognostic factors ; timing of surgery
Settore MED/27 - Neurochirurgia
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/141951
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