The invention concerns biomimetic peptides having a common pentapeptide sequence, which allow bone regeneration by activating the hydroxyapatite (Hap) deposition process. Their uses as a medicament, and specifically in the field of bone, dental (dentin and enamel) and periodontal regeneration, and in the functionalization of prostheses, screws, fixings, inserts or supports made of metal, ceramic, or natural or synthetic polymeric material are also described. Further described are a pharmaceutical composition and a cosmetic composition comprising such peptides, the use as a medicament, in bone, dental and periodontal regeneration, its cosmetic use and its use in the functionalization of prostheses, screws, fixings, inserts or supports made of metal, ceramic, or natural or synthetic polymeric material are further described.

BIOMIMETIC PEPTIDES AND THEIR USE IN BONE REGENERATION / M. Biagiotti, G. Freddi, A. Alessandrino, M. Sironi, S. Pieraccini, F. Dapiaggi.

BIOMIMETIC PEPTIDES AND THEIR USE IN BONE REGENERATION

M. Biagiotti;M. Sironi;S. Pieraccini;F. Dapiaggi
2025

Abstract

The invention concerns biomimetic peptides having a common pentapeptide sequence, which allow bone regeneration by activating the hydroxyapatite (Hap) deposition process. Their uses as a medicament, and specifically in the field of bone, dental (dentin and enamel) and periodontal regeneration, and in the functionalization of prostheses, screws, fixings, inserts or supports made of metal, ceramic, or natural or synthetic polymeric material are also described. Further described are a pharmaceutical composition and a cosmetic composition comprising such peptides, the use as a medicament, in bone, dental and periodontal regeneration, its cosmetic use and its use in the functionalization of prostheses, screws, fixings, inserts or supports made of metal, ceramic, or natural or synthetic polymeric material are further described.
SILK BIOMATERIALS S.R.L.
US2025129123A1
US18/681,534
US18/681,534
24-apr-2025
Settore CHEM-07/A - Chimica farmaceutica
Settore CHEM-02/A - Chimica fisica
BIOMIMETIC PEPTIDES AND THEIR USE IN BONE REGENERATION / M. Biagiotti, G. Freddi, A. Alessandrino, M. Sironi, S. Pieraccini, F. Dapiaggi.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1242838
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