We present a case report of an 8-year-old African origin, Italian born girl, fully immunized for Diphtheria, with multiple ulcers caused by Corynebacterium diphtheria. The clinical event was preceded by a recent trip to Burkina Faso in a rural area. The atypical presentation with ulcers spread to the entire body and particularly to one leg, led to a bacterial swab, from whose culture the pathogen emerged. The girl was initially empirically treated with amoxicillin/clavulanate and then azithromycin. Cutaneous forms are the most common of all forms and have a relevant spreading role. This case is of particular concern in the context of a rising number of cases in Europe, and it’s peculiar since it doesn’t regard immigrants and refugees, whereas it regards a fully immunized child who traveled from an endemical country.

Cutaneous diphtheria in a child returning from visiting friends & relatives in Burkina Faso: a case report / G. Pagani, M. Ticozzelli, F. Bassani, S. Sciarrabba, R. Agistri, L. Pogliani, B. Osnaghi, C. Pavia, L. Vismara, S. Rusconi. - In: INFECTION. - ISSN 0300-8126. - (2025). [10.1007/s15010-025-02636-3]

Cutaneous diphtheria in a child returning from visiting friends & relatives in Burkina Faso: a case report

M. Ticozzelli;F. Bassani
;
S. Sciarrabba;L. Pogliani;C. Pavia;L. Vismara;S. Rusconi
Ultimo
2025

Abstract

We present a case report of an 8-year-old African origin, Italian born girl, fully immunized for Diphtheria, with multiple ulcers caused by Corynebacterium diphtheria. The clinical event was preceded by a recent trip to Burkina Faso in a rural area. The atypical presentation with ulcers spread to the entire body and particularly to one leg, led to a bacterial swab, from whose culture the pathogen emerged. The girl was initially empirically treated with amoxicillin/clavulanate and then azithromycin. Cutaneous forms are the most common of all forms and have a relevant spreading role. This case is of particular concern in the context of a rising number of cases in Europe, and it’s peculiar since it doesn’t regard immigrants and refugees, whereas it regards a fully immunized child who traveled from an endemical country.
Cutaneous; Diphtheria; Emerging; Epidemiology
Settore MEDS-10/B - Malattie infettive
2025
set-2025
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1196117
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