In swine farming, animals develop diseases that require the use of antibiotics. In‑feed antibiotics as growth promoters have been banned due to the increasing concern of antimicrobial resistance. Seaweeds offer bioactive molecules with antibacterial and antioxidant properties. The aim was to estimate the in vitro properties of seaweed extracts: Ascophyllum nodosum (AN), Palmaria palmata (PP), Ulva lactuca (UL), and 1:1 mixes (ANPP, ANUL, PPUL). Escherichia coli strains were used to test for growth inhibitory activity, and chemical‑based assays were performed for antioxidant properties. The treatments were 2 (with/without Escherichia coli) × 2 (F4 + and F18 +) × 5 doses (0, 1.44, 2.87, 5.75, 11.50, and 23.0 mg/mL). Bacteria were supplemented with seaweed extracts, and growth was monitored. The antioxidant activity was assessed with 6 doses (0, 1, 50, 100, 200, 500, and 600 mg/ mL) × 6 compounds using two chemical assays. Data were evaluated through SAS. The results showed that AN and UL significantly inhibited (p < 0.05) the growth of F4 + and F18 +. PP and mixes did not display an inhibition of the bacteria growth. AN, PP, UL extracts, and mixes exhibited antioxidant activities, with AN showing the strongest dose–response. Thus, AN and UL seaweed extracts reveal promising antibacterial and antioxidant effects and may be candidates for in‑feed additives.

Assessment of the antibacterial and antioxidant activities of seaweed-derived extracts / M. Hejna, M. Dell'Anno, Y. Liu, L. Rossi, A. Aksmann, G. Pogorzelski, A. Jóźwik. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 14:1(2024), pp. 21044.1-21044.15. [10.1038/s41598-024-71961-8]

Assessment of the antibacterial and antioxidant activities of seaweed-derived extracts

M. Dell'Anno
Secondo
;
L. Rossi;
2024

Abstract

In swine farming, animals develop diseases that require the use of antibiotics. In‑feed antibiotics as growth promoters have been banned due to the increasing concern of antimicrobial resistance. Seaweeds offer bioactive molecules with antibacterial and antioxidant properties. The aim was to estimate the in vitro properties of seaweed extracts: Ascophyllum nodosum (AN), Palmaria palmata (PP), Ulva lactuca (UL), and 1:1 mixes (ANPP, ANUL, PPUL). Escherichia coli strains were used to test for growth inhibitory activity, and chemical‑based assays were performed for antioxidant properties. The treatments were 2 (with/without Escherichia coli) × 2 (F4 + and F18 +) × 5 doses (0, 1.44, 2.87, 5.75, 11.50, and 23.0 mg/mL). Bacteria were supplemented with seaweed extracts, and growth was monitored. The antioxidant activity was assessed with 6 doses (0, 1, 50, 100, 200, 500, and 600 mg/ mL) × 6 compounds using two chemical assays. Data were evaluated through SAS. The results showed that AN and UL significantly inhibited (p < 0.05) the growth of F4 + and F18 +. PP and mixes did not display an inhibition of the bacteria growth. AN, PP, UL extracts, and mixes exhibited antioxidant activities, with AN showing the strongest dose–response. Thus, AN and UL seaweed extracts reveal promising antibacterial and antioxidant effects and may be candidates for in‑feed additives.
Seaweeds extracts; Bioactive compounds; Antibacterial; Antioxidant; Livestock farming
Settore AGR/18 - Nutrizione e Alimentazione Animale
   Polish Academy of Sciences’ Individual Fellowships: Innovation & Creativity
   PASIFIC
   European Commission
   Horizon 2020 Framework Programme
   847639
2024
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1095929
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